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Select clones of interest on the basis QC metrics

Usage

select_clones(
  sce,
  ADO_cut = 0.1,
  GQ_cut = 30,
  DP_cut = 10,
  select_exact = FALSE
)

Arguments

sce

a SingleCellExperiment object containing the Clones,Architecture, and NGT matrix

ADO_cut

maximum median allele dropout

GQ_cut

mimimum median gene quality score

DP_cut

minimum median sequencing depth

select_exact

default=FALSE, can supply a vector of clones of interest to bypass QC filtering

Value

a subset of the sce object